SCHEMBL31330724

SCHEMBL31330724

N#Cc1ccc(OC2CCC(N)CC2)c2cccnc12

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 12/20 0.49
TLR8 Q9NR97 1/20 0.45
TBK1 Q9UHD2 6/20 0.41
IKBKE Q14164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23142962 1.00 AR (0.49) ARTLR8TBK1IKBKE
SCHEMBL23142905 1.00 AR (0.49) ARTLR8TBK1IKBKE
SCHEMBL23171849 1.00 AR (0.49) ARTLR8TBK1IKBKE
Hydrochloric Acid SCHEMBL23117057 0.99 AR (0.48) ARTLR8TBK1IKBKE
Hydrochloric Acid SCHEMBL23117059 0.99 AR (0.48) ARTLR8TBK1IKBKE
SCHEMBL31330985 0.84 AR (0.39) ARTBK1IKBKE
SCHEMBL23117208 0.81 AR (0.63) ARTBK1
SCHEMBL23117210 0.81 AR (0.63) ARTBK1
SCHEMBL22661302 0.78 TLR8 (0.40) ARTLR8
SCHEMBL22661297 0.78 TLR8 (0.40) ARTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025011623-A1 CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海壹迪生物技术有限公司 2025-01-16 WO disclosed