SCHEMBL31330985

SCHEMBL31330985

N#Cc1ccc(OC2CCC(N)CC2)c2nccnc12

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 0.39
TBK1 Q9UHD2 8/20 0.37
IKBKE Q14164 4/20 0.37
XDH P47989 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31330724 0.84 AR (0.49) ARTBK1IKBKE
SCHEMBL23142962 0.84 AR (0.49) ARTBK1IKBKE
SCHEMBL23171849 0.84 AR (0.49) ARTBK1IKBKE
SCHEMBL23142905 0.84 AR (0.49) ARTBK1IKBKE
Hydrochloric Acid SCHEMBL23117059 0.83 AR (0.48) ARTBK1IKBKE
Hydrochloric Acid SCHEMBL23117057 0.83 AR (0.48) ARTBK1IKBKE
SCHEMBL31330782 0.79 AR (0.52) ARTBK1IKBKE
SCHEMBL16989684 0.76 TRPC3 (0.44)
SCHEMBL16989683 0.76 TRPC3 (0.44)
SCHEMBL24247772 0.74 GPR6 (0.40) TBK1IKBKEXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025011623-A1 CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海壹迪生物技术有限公司 2025-01-16 WO disclosed