Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 18/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 15/20 | 0.49 |
| ▸ | SMARCA4 | P51532 | 15/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 8/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331350 | 0.91 | PBRM1 (0.38) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31331332 | 0.87 | PBRM1 (0.51) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31101965 | 0.81 | PBRM1 (0.53) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31103132 | 0.80 | PBRM1 (0.52) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31279425 | 0.79 | DRD2 (0.47) | HTR1ADRD2 | |
| SCHEMBL31100500 | 0.79 | PBRM1 (0.50) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31279160 | 0.79 | DRD2 (0.48) | HTR1ADRD2 | |
| SCHEMBL31279201 | 0.79 | DRD2 (0.39) | HTR1ADRD2 | |
| SCHEMBL31278962 | 0.78 | DRD4 (0.50) | HTR1ADRD2 | |
| SCHEMBL31458542 | 0.78 | DDB1 (0.47) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024245443-A1 | COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | claimed |
| WO-2024245443-A1 | COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |