Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331952 | 0.88 | TNNI3K (0.47) | TEAD1YAP1TNNI3KMAPT | |
| SCHEMBL31331820 | 0.84 | TNNI3K (0.46) | TEAD1YAP1TNNI3KMAP3K12MAPT | |
| SCHEMBL22718177 | 0.82 | TEAD1 (0.55) | TEAD1YAP1TNNI3KMAP3K12MAPT | |
| SCHEMBL31332132 | 0.80 | CDK5 (0.40) | MAP3K12SYK | |
| SCHEMBL20779719 | 0.73 | TEAD1 (0.74) | TEAD1YAP1TNNI3KMAPT | |
| SCHEMBL20766734 | 0.73 | TEAD1 (0.60) | TEAD1YAP1TNNI3KMAPT | |
| SCHEMBL29901824 | 0.73 | TEAD1 (0.60) | TEAD1YAP1TNNI3KMAPT | |
| SCHEMBL22843401 | 0.71 | TEAD1 (0.39) | TEAD1YAP1MAP3K12SYK | |
| SCHEMBL22718131 | 0.70 | TEAD1 (0.58) | TEAD1YAP1TNNI3KMAPT | |
| SCHEMBL31331799 | 0.69 | CCR6 (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |