Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 6/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.40 |
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | NEK4 | P51957 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.35 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331799 | 0.90 | CCR6 (0.41) | CDK5CDK5R1CNR1CNR2 | |
| SCHEMBL31331755 | 0.87 | CDK5 (0.41) | CDK5CDK5R1CNR1CNR2 | |
| SCHEMBL22718287 | 0.85 | CDK5 (0.38) | CDK5CDK5R1SYKKDRCLK2 | |
| SCHEMBL31331704 | 0.80 | TEAD1 (0.41) | SYKMAP3K12 | |
| SCHEMBL31331877 | 0.77 | CDK5 (0.39) | CDK5CDK5R1 | |
| SCHEMBL22718447 | 0.75 | CCR6 (0.44) | CDK5CDK5R1 | |
| SCHEMBL31331781 | 0.75 | LIPE (0.41) | CDK5CDK5R1 | |
| SCHEMBL22718289 | 0.74 | TEAD1 (0.47) | SYKKDRCLK2IRAK1NEK4 | |
| SCHEMBL29438894 | 0.74 | TEAD1 (0.47) | SYKKDRCLK2IRAK1NEK4 | |
| SCHEMBL22718316 | 0.73 | CCR6 (0.43) | CDK5CDK5R1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |