Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 7/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331766 | 0.90 | KDM1A (0.46) | KDM4EKDM1AKITHRH4HRH3 | |
| SCHEMBL31331727 | 0.87 | KDM1A (0.44) | KDM4EKDM1AKITUSP2ALDH1A1 | |
| SCHEMBL31331652 | 0.86 | KDM1A (0.48) | KDM4ETP53KDM1APGRKIT | |
| SCHEMBL31331857 | 0.84 | KDM1A (0.46) | KDM4ETP53KDM1APGRSSTR2 | |
| SCHEMBL31331825 | 0.80 | DRD2 (0.37) | KDM1ANAMPTDRD2 | |
| SCHEMBL31331861 | 0.76 | KDM1A (0.54) | KDM1AKITSSTR2 | |
| SCHEMBL31331740 | 0.76 | KDM1A (0.54) | KDM1AKITSSTR2 | |
| SCHEMBL31331989 | 0.75 | KDM1A (0.48) | KDM1AKITSSTR2CYP3A4 | |
| SCHEMBL31331889 | 0.74 | KDM1A (0.52) | KDM1A | |
| SCHEMBL31331682 | 0.74 | KDM1A (0.52) | KDM1AKITHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285613-A | Substituted quinoxaline and quinazolinone compounds and uses thereof | 河南中医药大学 | 2025-01-10 | — | — | CN | claimed |
| CN-119285613-A | Substituted quinoxaline and quinazolinone compounds and uses thereof | 河南中医药大学 | 2025-01-10 | — | — | CN | disclosed |