Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668344 | 0.86 | ALDH1A1 (0.54) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL28404415 | 0.83 | ALDH1A1 (0.66) | TDP1ALDH1A1CYP3A4HPGDPRKAB2 | |
| SCHEMBL14992 | 0.83 | CYP3A4 (1.00) | TDP1ALDH1A1CYP3A4HPGDPTPRC | |
| SCHEMBL29350162 | 0.83 | CYP3A4 (1.00) | TDP1ALDH1A1CYP3A4HPGDPTPRC | |
| SCHEMBL5483295 | 0.79 | HPGD (0.90) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL1457541 | 0.78 | ALDH1A1 (0.56) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL7159670 | 0.78 | ALDH1A1 (0.56) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL1070288 | 0.77 | CYP3A4 (0.69) | TDP1ALDH1A1CYP3A4HPGDCHEK1 | |
| SCHEMBL6357932 | 0.77 | ALDH1A1 (0.69) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL11663956 | 0.76 | CYP3A4 (0.68) | TDP1ALDH1A1CYP3A4HPGDCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043588-A1 | SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER | BASF SE (DE) | 2010-04-22 | — | — | WO | claimed |