Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26669327 | 0.79 | TEAD1 (0.42) | LMNATEAD1GAAEGFRYAP1 | |
| SCHEMBL29438936 | 0.76 | TEAD1 (0.59) | LMNAARTEAD1KDM4EGAA | |
| SCHEMBL22718028 | 0.76 | TEAD1 (0.59) | LMNAARTEAD1KDM4EGAA | |
| SCHEMBL22829731 | 0.73 | EGFR (0.41) | GAASYKEGFR | |
| SCHEMBL31332045 | 0.73 | EGFR (0.41) | GAASYKEGFR | |
| SCHEMBL22843433 | 0.72 | MAPT (0.47) | LMNAARTEAD1KDM4EGAA | |
| SCHEMBL20766513 | 0.71 | TEAD1 (0.80) | TEAD1KDM4EGAAEGFRYAP1 | |
| SCHEMBL22719814 | 0.70 | TEAD1 (0.58) | TEAD1KDM4EGAAEGFRYAP1 | |
| SCHEMBL29504930 | 0.70 | TEAD1 (0.58) | TEAD1KDM4EGAAEGFRYAP1 | |
| SCHEMBL26669315 | 0.69 | PDE2A (0.37) | LMNAGAAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |