SCHEMBL31332426

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CS)C(=O)NCC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	PTH1R	Q03431	2/20	0.54

▸	TFPI	P10646	1/20	0.54

▸	VIPR2	P41587	5/20	0.53

▸	VIPR1	P32241	3/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31332249	0.98	PTH1R (0.55)	PTH1RTFPIVIPR2VIPR1
SCHEMBL31332423	0.98	PTH1R (0.55)	PTH1RTFPIVIPR2VIPR1
SCHEMBL29863205	0.95	OPRM1 (0.53)	PTH1RTFPI
SCHEMBL31332065	0.94	PTH1R (0.60)	PTH1R
SCHEMBL31332037	0.94	TFPI (0.55)	PTH1RTFPIVIPR2VIPR1
SCHEMBL29863200	0.93	PTH1R (0.61)	PTH1RTFPIVIPR1
SCHEMBL29863068	0.91	PTH1R (0.62)	PTH1RTFPIVIPR1
SCHEMBL30906439	0.91	VIPR1 (0.58)	PTH1RTFPIVIPR2VIPR1
SCHEMBL30906502	0.91	VIPR1 (0.58)	PTH1RTFPIVIPR2VIPR1
SCHEMBL29862843	0.90	PTH1R (0.57)	PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119529033-A	Ultra-long-acting polypeptide for NPR-B targeting and application thereof in skeletal system diseases	中山大学	2025-02-28	—	—	CN	disclosed