Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451197 | 1.00 | FFAR3 (0.37) | FFAR3TSHRNFKB1CYP2C19DPP4 | |
| SCHEMBL15125244 | 1.00 | FFAR3 (0.37) | FFAR3TSHRNFKB1CYP2C19DPP4 | |
| SCHEMBL17157143 | 0.94 | FFAR3 (0.36) | FFAR3 | |
| SCHEMBL17157141 | 0.94 | FFAR3 (0.36) | FFAR3 | |
| SCHEMBL22208430 | 0.86 | FFAR3 (0.40) | FFAR3 | |
| SCHEMBL2682019 | 0.85 | CYP3A4 (0.40) | FFAR3 | |
| SCHEMBL2682939 | 0.85 | CYP3A4 (0.40) | FFAR3 | |
| SCHEMBL2682021 | 0.85 | CYP3A4 (0.40) | FFAR3 | |
| SCHEMBL6761647 | 0.85 | FFAR3 (0.31) | FFAR3 | |
| SCHEMBL29191746 | 0.83 | FFAR3 (0.34) | FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107072993-B | Pharmaceutical containing sodium-dependent phosphate transporter inhibitor | 中外制药株式会社 | 2021-02-12 | — | — | CN | disclosed |
| CN-104877001-B | Antifungal formulations | 西尼克斯公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-102176828-B | Antifungal preparation | SCYNEXIS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-104877001-A | Antifungal Agents | SCYNEXIS INC | 2015-09-02 | — | — | CN | disclosed |
| CN-102176827-B | Antifungal formulations | SCYNEXIS INC | 2015-05-20 | — | — | CN | disclosed |
| EP-2326180-B1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME (US) | 2013-10-16 | — | — | EP | disclosed |
| US-8188085-B2 | Antifungal agents | MERCK SHARP & DOHME CORP. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100113439-A1 | Antifungal agents | MERCK & CO., INC. (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2010019204-A1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-02-18 | — | — | WO | disclosed |
| EP-0618221-A2 | Heterocyclic inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113439-A1 | Antifungal agents | GMDS, GBA3, UGGT1 | FFAR3 1958/4885TSHR 4815/4885NFKB1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.