SCHEMBL31332735

SCHEMBL31332735

CCOc1cccc(NC(=O)NCC(C)(OC)c2cccc(Cl)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 1/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
LMNA P02545 2/20 0.46
HTT P42858 4/20 0.45
EPHX1 P07099 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
HSD17B10 Q99714 1/20 0.44
RAF1 P04049 1/20 0.43
BRAF P15056 1/20 0.43
NR1H4 Q96RI1 1/20 0.43
MITF O75030 1/20 0.43
PAX8 Q06710 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
MAPT P10636 2/20 0.42
MAPK1 P28482 1/20 0.42
STAT1 P42224 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31332681 0.91 HTT (0.55) KMT2AMEN1NPC1RAB9ALMNA
SCHEMBL31332621 0.91 HTT (0.55) KMT2AMEN1NPC1RAB9ALMNA
SCHEMBL31332672 0.87 P2RX1 (0.50) NPC1RAB9ALMNAHTTSMN1; SMN2
SCHEMBL31332776 0.85 ALDH1A1 (0.51) KMT2AMEN1NPC1RAB9ALMNA
SCHEMBL4118559 0.80 MEN1 (0.66) FADS1KMT2AMEN1NPC1RAB9A
SCHEMBL31332818 0.76 EPHX1 (0.50) EPHX1MAPT
SCHEMBL4106738 0.74 NPC1 (0.64) KMT2AMEN1NPC1RAB9ALMNA
SCHEMBL31332799 0.73 POLB (0.53) KMT2AMEN1NPC1RAB9AHTT
SCHEMBL6690315 0.73 HTT (0.55) KMT2ANPC1RAB9AHTTEPHX1
SCHEMBL31332653 0.72 EPHX2 (0.49) KMT2AMEN1NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709708-A1 NOVEL CARBOXAMIDE DERIVATIVES ANGELINI PHARMA S.P.A. (IT) 2026-03-18 EP disclosed
WO-2024233603-A1 NOVEL CARBOXAMIDE DERIVATIVES ICAGEN, LLC (US) 2024-11-14 WO disclosed