SCHEMBL31333191

SCHEMBL31333191

O=C1CCC(Nc2ccc(C3CCN([C@H]4CC[C@H](NC(=O)[C@H]5CC[C@H](Nc6ncc(F)c(-c7ccnc(-n8ccccc8=O)c7)n6)CC5)CC4)CC3)c(F)c2)C(=O)N1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 4/20 0.32
DDB1 Q16531 3/20 0.32
CSF1R P07333 4/20 0.31
CDK4 P11802 4/20 0.31
CDK6 Q00534 4/20 0.31
PIK3CD O00329 3/20 0.31
MAPK8 P45983 1/20 0.31
MAPK1 P28482 1/20 0.31
SYK P43405 1/20 0.31
CCNT1 O60563 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
CDK9 P50750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334509 1.00 CRBN (0.32) CRBNDDB1CSF1RCDK4CDK6
SCHEMBL31333441 0.93 SYK (0.34) CRBNDDB1CSF1RCDK4CDK6
SCHEMBL31333423 0.93 SYK (0.34) CRBNDDB1CSF1RCDK4CDK6
SCHEMBL31333340 0.93 SYK (0.34) CRBNDDB1CSF1RCDK4CDK6
SCHEMBL31333967 0.93 SYK (0.34) CRBNDDB1CSF1RCDK4CDK6
SCHEMBL31334042 0.93 SYK (0.34) CRBNDDB1CSF1RCDK4CDK6
SCHEMBL31333992 0.93 SYK (0.34) CRBNDDB1CSF1RCDK4CDK6
SCHEMBL31334923 0.93 SYK (0.34) CRBNDDB1CSF1RCDK4CDK6
SCHEMBL31334087 0.92 DDB1 (0.32) CRBNDDB1MAPK8SYK
SCHEMBL31334619 0.89 DDB1 (0.35) CRBNDDB1CSF1RCDK4CDK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed