Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | CSF1R | P07333 | 5/20 | 0.32 |
| ▸ | CDK4 | P11802 | 5/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.30 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.30 |
| ▸ | CCNK | O75909 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CCNH | P51946 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334923 | 1.00 | SYK (0.34) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31334042 | 1.00 | SYK (0.34) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31333967 | 1.00 | SYK (0.34) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31333992 | 1.00 | SYK (0.34) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31333423 | 1.00 | SYK (0.34) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31333340 | 1.00 | SYK (0.34) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31333191 | 0.93 | CRBN (0.32) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31334509 | 0.93 | CRBN (0.32) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31333963 | 0.92 | MEN1 (0.35) | SYKCSF1RCDK4CDK6PIK3CD | |
| SCHEMBL31335037 | 0.92 | MEN1 (0.35) | SYKCSF1RCDK4CDK6PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |