SCHEMBL31333324

SCHEMBL31333324

Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(C3CCN(CCN4CCC(C(=O)OC(C)(C)C)CC4)CC3)cc21

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 10/20 0.49
▸ CRBN Q96SW2 10/20 0.49
▸ IKZF2 Q9UKS7 8/20 0.40
▸ IKZF1 Q13422 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30289048 0.89 DDB1 (0.47) DDB1CRBNIKZF2IKZF1
SCHEMBL31323566 0.89 DDB1 (0.51) DDB1CRBNIKZF2IKZF1HDAC8
SCHEMBL22502565 0.89 DDB1 (0.50) DDB1CRBNIKZF2IKZF1
SCHEMBL23540861 0.89 DDB1 (0.52) DDB1CRBNIKZF2IKZF1HDAC8
SCHEMBL23541289 0.89 DDB1 (0.52) DDB1CRBNIKZF2IKZF1HDAC8
SCHEMBL31333960 0.88 DDB1 (0.54) DDB1CRBNIKZF2IKZF1
SCHEMBL30288962 0.88 DDB1 (0.49) DDB1CRBNIKZF2IKZF1
SCHEMBL22525513 0.88 DDB1 (0.49) DDB1CRBNIKZF2IKZF1HDAC8
SCHEMBL30289409 0.87 DDB1 (0.44) DDB1CRBNIKZF2IKZF1HDAC8
SCHEMBL23540374 0.87 DDB1 (0.50) DDB1CRBNIKZF2IKZF1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
Send feedback