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Sugi Predict / Compounds / SCHEMBL31333339

SCHEMBL31333339

SCHEMBL31333339

Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(C3CCN(CCC4CCN(C(=O)[C@H]5CCC[C@@H](Nc6ncc(Cl)c(-c7cccc(-c8ccccc8)c7)n6)C5)CC4)CC3)cc21

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 16/20 0.38
▸ CRBN Q96SW2 4/20 0.35
▸ CDK12 Q9NYV4 1/20 0.35
▸ DDB1 Q16531 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31335057 1.00 MAPK1 (0.38) MAPK1CRBNCDK12DDB1
SCHEMBL31334521 1.00 MAPK1 (0.38) MAPK1CRBNCDK12DDB1
SCHEMBL31335081 0.96 MAPK1 (0.36) MAPK1CRBNCDK12DDB1
SCHEMBL31333262 0.95 MAPK1 (0.38) MAPK1CRBNCDK12DDB1
SCHEMBL31334174 0.93 MAPK1 (0.40) MAPK1CRBNDDB1
SCHEMBL31333312 0.93 MAPK1 (0.41) MAPK1
SCHEMBL31333237 0.93 MAPK1 (0.42) MAPK1
SCHEMBL31334794 0.90 MAPK1 (0.41) MAPK1CRBNDDB1
SCHEMBL31334132 0.89 MAPK1 (0.37) MAPK1CRBNDDB1
SCHEMBL31334674 0.88 CRBN (0.39) MAPK1CRBNCDK12DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed