SCHEMBL31333484

SCHEMBL31333484

CC(C)(C)OC(=O)N1CCN(CC2CCN(c3ccc4c(c3)oc(=O)n4C3CCC(=O)NC3=O)CC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 13/20 0.48
DDB1 Q16531 9/20 0.48
AR P10275 3/20 0.42
CNR1 P21554 1/20 0.40
ESR1 P03372 1/20 0.38
GPR119 Q8TDV5 3/20 0.38
CDK9 P50750 1/20 0.37
TGFBR1 P36897 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333525 0.97 CRBN (0.48) CRBNDDB1ARCNR1ESR1
SCHEMBL30831040 0.91 CRBN (0.54) CRBNDDB1GPR119
SCHEMBL31333265 0.90 CRBN (0.47) CRBNDDB1GPR119TGFBR1
SCHEMBL31333449 0.89 CRBN (0.43) CRBNDDB1ARESR1CDK9
SCHEMBL31333783 0.87 CRBN (0.42) CRBNDDB1ARESR1CDK9
SCHEMBL31282043 0.87 CRBN (0.49) CRBNDDB1ARCNR1GPR119
SCHEMBL31334328 0.87 CRBN (0.40) CRBNDDB1ARESR1CDK9
SCHEMBL30830887 0.87 CRBN (0.47) CRBNDDB1GPR119
SCHEMBL31333308 0.86 DDB1 (0.48) CRBNDDB1GPR119
SCHEMBL25928709 0.86 DDB1 (0.45) CRBNDDB1GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed