Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND2 | P30279 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30831040 | 0.92 | CRBN (0.54) | DDB1CRBNPDK2GPR119MAPT | |
| SCHEMBL30830887 | 0.86 | CRBN (0.47) | DDB1CRBNGPR119NAMPT | |
| SCHEMBL31333525 | 0.86 | CRBN (0.48) | DDB1CRBNGPR119 | |
| SCHEMBL31333484 | 0.86 | CRBN (0.48) | DDB1CRBNGPR119 | |
| SCHEMBL31333265 | 0.83 | CRBN (0.47) | DDB1CRBNGPR119 | |
| SCHEMBL23541035 | 0.78 | DDB1 (0.54) | DDB1CRBNGPR119MAPTNAMPT | |
| SCHEMBL30768477 | 0.77 | DDB1 (0.55) | DDB1CRBNPDK2GPR119MAPT | |
| SCHEMBL22835971 | 0.77 | DDB1 (0.55) | DDB1CRBNPDK2GPR119MAPT | |
| SCHEMBL30768650 | 0.77 | DDB1 (0.55) | DDB1CRBNPDK2GPR119MAPT | |
| SCHEMBL24793535 | 0.77 | LMNA (0.50) | PDK2GPR119MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |