Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334596 | 0.88 | ADORA1 (0.41) | MAPK1CTSAIRAK4CDK2ADORA1 | |
| SCHEMBL31333640 | 0.88 | MAPK1 (0.44) | MAPK8MAPK14MAPK1CDK2CCNA2 | |
| SCHEMBL31334522 | 0.88 | CTSA (0.41) | MAPK1MCHR1CTSACDK2ADORA1 | |
| SCHEMBL31333196 | 0.88 | MAPK3 (0.42) | MAPK1CTSACDK2ADORA1CCNA2 | |
| SCHEMBL31333452 | 0.84 | MAPK8 (0.50) | MAPK8MAPK14MAPK1MCHR1CDK2 | |
| SCHEMBL31334884 | 0.82 | MAPK3 (0.43) | MAPK8MAPK1CTSACDK2ADORA1 | |
| SCHEMBL31334493 | 0.82 | MAPK8 (0.43) | MAPK8MAPK14MAPK1MCHR1CDK2 | |
| SCHEMBL31334606 | 0.82 | MAPK3 (0.40) | MAPK8MAPK1CTSACDK2ADORA1 | |
| SCHEMBL31334783 | 0.81 | MAPK8 (0.45) | MAPK8MAPK14MAPK1MCHR1CDK2 | |
| SCHEMBL31334517 | 0.81 | CSNK2A2 (0.49) | MAPK8MAPK14MCHR1ADORA1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |