SCHEMBL31333640

SCHEMBL31333640

CC(=O)N1CCC(Nc2ncc(F)c(-c3cccc(C4(O)COC4)c3)n2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.44
DYRK2 Q92630 4/20 0.44
MAPK3 P27361 2/20 0.43
CDK2 P24941 7/20 0.43
CCNA2 P20248 4/20 0.43
CCNA1 P78396 4/20 0.43
CDK1 P06493 3/20 0.43
CCNB1 P14635 2/20 0.43
CCNE1 P24864 2/20 0.43
CDK5 Q00535 2/20 0.43
CDK5R1 Q15078 2/20 0.43
GSK3B P49841 2/20 0.43
MAPK14 Q16539 1/20 0.43
CCNB2 O95067 1/20 0.42
CCNE2 O96020 1/20 0.42
CCNB3 Q8WWL7 1/20 0.42
CDK4 P11802 2/20 0.41
CCND1 P24385 2/20 0.41
PRKD3 O94806 1/20 0.41
MAP4K4 O95819 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333489 0.88 MAPK8 (0.44) MAPK1MAPK3CDK2CCNA2CDK1
SCHEMBL31334596 0.85 ADORA1 (0.41) MAPK1DYRK2MAPK3CDK2CCNA2
SCHEMBL31334522 0.84 CTSA (0.41) MAPK1DYRK2MAPK3CDK2CCNA2
SCHEMBL31334440 0.84 IRAK1 (0.49) MAPK1DYRK2MAPK3CDK2CCNA2
SCHEMBL31333196 0.84 MAPK3 (0.42) MAPK1DYRK2MAPK3CDK2CCNA2
SCHEMBL31335060 0.82 MAPK1 (0.45) MAPK1DYRK2MAPK3CDK2CCNA2
SCHEMBL31333408 0.82 DYRK2 (0.48) MAPK1DYRK2MAPK3CDK2CCNA2
SCHEMBL31334222 0.82 JAK2 (0.51) MAPK1CDK2CCNA2CCNA1CDK1
SCHEMBL31334884 0.81 MAPK3 (0.43) MAPK1DYRK2MAPK3CDK2CCNA2
SCHEMBL31334873 0.80 CDK2 (0.47) MAPK1DYRK2MAPK3CDK2CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed