Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334033 | 0.97 | SYK (0.47) | SYKRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL31334893 | 0.90 | SYK (0.46) | SYKRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL31333482 | 0.89 | SYK (0.48) | SYKRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL31334316 | 0.89 | MAPK1 (0.46) | SYKRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL31334815 | 0.88 | MAP4K1 (0.45) | MAPK1CDK2CCNE1CDK1CCNB2 | |
| SCHEMBL31334318 | 0.88 | SYK (0.45) | SYKRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL31334927 | 0.88 | MAP4K1 (0.45) | MAPK1CDK2CCNE1CDK1CCNB2 | |
| SCHEMBL31334814 | 0.88 | SYK (0.49) | SYKRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL31334179 | 0.88 | SYK (0.48) | SYKRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL31333712 | 0.87 | SYK (0.47) | SYKRAB9ANPC1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |