SCHEMBL31333712

SCHEMBL31333712

O=C1CCCCN1c1cccc(-c2nc(N[C@H]3CC[C@H](O)CC3)ncc2F)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 5/20 0.47
ADORA1 P30542 4/20 0.44
ADORA2A P29274 3/20 0.43
ADORA2B P29275 1/20 0.43
MAPK8 P45983 4/20 0.41
MAPK1 P28482 2/20 0.40
MAPK9 P45984 3/20 0.39
MAPK10 P53779 2/20 0.39
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39
CCNB2 O95067 1/20 0.39
CCNE2 O96020 1/20 0.39
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CCNE1 P24864 1/20 0.39
CDK2 P24941 1/20 0.39
CDK5 Q00535 1/20 0.39
CDK5R1 Q15078 1/20 0.39
CCNB3 Q8WWL7 1/20 0.39
MAPK14 Q16539 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334552 0.92 SYK (0.44) SYKADORA1MAPK8MAPK1MAPK9
SCHEMBL31333873 0.91 SYK (0.49) SYKMAPK8MAPK1MAPK9MAPK10
SCHEMBL31335030 0.91 SYK (0.49) SYKADORA1MAPK1MAPK10CCNB2
SCHEMBL31333530 0.91 SYK (0.49) SYKADORA1MAPK1MAPK10CCNB2
SCHEMBL31334033 0.90 SYK (0.47) SYKMAPK8MAPK1MAPK9MAPK10
SCHEMBL31334567 0.90 SYK (0.50) SYKMAPK1MAPK10CCNB2CCNE2
SCHEMBL31335040 0.90 SYK (0.50) SYKMAPK1MAPK10CCNB2CCNE2
SCHEMBL31334120 0.89 SYK (0.45) SYKMAPK8MAPK1CCNB2CCNE2
SCHEMBL31334179 0.88 SYK (0.48) SYKMAPK8MAPK1MAPK9MAPK10
SCHEMBL31333482 0.88 SYK (0.48) SYKMAPK1MAPK9GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed