Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF1 | Q13422 | 3/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 12/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333787 | 0.94 | IKZF1 (0.52) | IKZF1IKZF2DDB1CRBN | |
| SCHEMBL31334252 | 0.94 | IKZF2 (0.51) | IKZF1IKZF2MAPK1 | |
| SCHEMBL31333738 | 0.94 | IKZF1 (0.51) | IKZF1IKZF2MAPK1 | |
| SCHEMBL31333218 | 0.93 | IKZF1 (0.49) | IKZF1IKZF2MAPK1DDB1CRBN | |
| SCHEMBL31333415 | 0.91 | IKZF1 (0.53) | IKZF1IKZF2MAPK1 | |
| SCHEMBL31334864 | 0.90 | IKZF1 (0.52) | IKZF1IKZF2MAPK1 | |
| SCHEMBL31333647 | 0.85 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL31334745 | 0.85 | MAPK1 (0.42) | IKZF1IKZF2MAPK1CRBN | |
| SCHEMBL31334853 | 0.85 | MAPK1 (0.43) | IKZF2MAPK1 | |
| SCHEMBL31333416 | 0.84 | IKZF1 (0.52) | IKZF1IKZF2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |