SCHEMBL31333738

SCHEMBL31333738

O=C1CCC(N2Cc3cc(C4CCN(CC(=O)N5CCN(C(=O)C6CCCC(Nc7ncc(Cl)c(-c8cccc(-c9ccccc9)c8)n7)C6)CC5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IKZF1 Q13422 4/20 0.51
IKZF2 Q9UKS7 12/20 0.47
MAPK1 P28482 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333787 0.95 IKZF1 (0.52) IKZF1IKZF2
SCHEMBL31333656 0.94 IKZF1 (0.49) IKZF1IKZF2MAPK1
SCHEMBL31334252 0.93 IKZF2 (0.51) IKZF1IKZF2MAPK1
SCHEMBL31334864 0.93 IKZF1 (0.52) IKZF1IKZF2MAPK1
SCHEMBL31333218 0.92 IKZF1 (0.49) IKZF1IKZF2MAPK1
SCHEMBL31333416 0.89 IKZF1 (0.52) IKZF1IKZF2MAPK1
SCHEMBL31333647 0.89 MAPK1 (0.44) MAPK1
SCHEMBL31333415 0.89 IKZF1 (0.53) IKZF1IKZF2MAPK1
SCHEMBL31333570 0.89 IKZF1 (0.49) IKZF1IKZF2MAPK1
SCHEMBL31333989 0.86 MAPK1 (0.46) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed