SCHEMBL31333771

SCHEMBL31333771

CC(C)(C)OC(=O)CC1(O)CCN(c2ccc(OCc3ccccc3)cc2F)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM5 P41594 1/20 0.42
▸ PDK2 Q15119 1/20 0.39
▸ YAP1 P46937 2/20 0.39
▸ MRGPRX4 Q96LA9 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ GAA P10253 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ GHSR Q92847 3/20 0.38
▸ SLC6A9 P48067 1/20 0.38
▸ HRH3 Q9Y5N1 2/20 0.38
▸ MAOB P27338 2/20 0.38
▸ LTA4H P09960 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ CHRM4 P08173 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334108 0.82 MAPT (0.38) ALDH1A1GAATSHRKMT2AMEN1
SCHEMBL23538920 0.81 FFAR4 (0.37) GRM5KMT2ASLC6A9
SCHEMBL29744929 0.81 FFAR4 (0.37) GRM5KMT2ASLC6A9
SCHEMBL8221363 0.81 GPR119 (0.53) GRM5YAP1ALDH1A1TSHRKMT2A
SCHEMBL25122064 0.81 MAPT (0.39) ALDH1A1GAATSHRKMT2AMEN1
SCHEMBL23551473 0.80 FFAR4 (0.41) ALDH1A1TSHRKMT2AMEN1MAPK1
SCHEMBL23539031 0.79 MAPT (0.38) ALDH1A1GAATSHRKMT2AMEN1
SCHEMBL29744638 0.79 MAPT (0.38) ALDH1A1GAATSHRKMT2AMEN1
SCHEMBL23538815 0.79 MAPT (0.42) ALDH1A1GAATSHRKMT2AMEN1
SCHEMBL29535010 0.79 MAPT (0.42) ALDH1A1GAATSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
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