Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334566 | 1.00 | PIK3CA (0.47) | PIK3CAAKT1JAK2MTORSYK | |
| SCHEMBL31333998 | 0.92 | SYK (0.48) | PIK3CAAKT1JAK2MTORSYK | |
| SCHEMBL31333243 | 0.91 | SYK (0.46) | SYKMAPK1CDK2CCNA2CCNT1 | |
| SCHEMBL31334207 | 0.90 | ADORA1 (0.45) | SYKMAPK1CDK2CCNA2CCNT1 | |
| SCHEMBL31333373 | 0.90 | AKT1 (0.49) | PIK3CAAKT1JAK2MTORSYK | |
| SCHEMBL31334186 | 0.89 | PIK3CA (0.47) | PIK3CAAKT1JAK2MTORSYK | |
| SCHEMBL31334203 | 0.89 | JAK2 (0.53) | PIK3CAAKT1JAK2MTORSYK | |
| SCHEMBL31333841 | 0.88 | MAP4K1 (0.44) | PIK3CAAKT1JAK2MTORSYK | |
| SCHEMBL31334599 | 0.87 | PIK3CA (0.46) | PIK3CAAKT1JAK2MTORSYK | |
| SCHEMBL31334913 | 0.87 | CDK2 (0.50) | PIK3CAAKT1JAK2MTORSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |