SCHEMBL31333970

SCHEMBL31333970

CC(C)(C)OC(=O)[C@H]1CC[C@H](N2CCN(c3ccc(NC4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 17/20 0.51
DDB1 Q16531 16/20 0.51
HRH3 Q9Y5N1 2/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333765 0.93 CRBN (0.49) CRBNDDB1HRH3
SCHEMBL25175940 0.91 CRBN (0.53) CRBNDDB1
SCHEMBL31334254 0.89 CRBN (0.49) CRBNDDB1HRH3
SCHEMBL31334487 0.88 CRBN (0.47) CRBNDDB1
SCHEMBL31333901 0.88 DDB1 (0.61) CRBNDDB1HRH3MAPT
SCHEMBL31334304 0.88 DDB1 (0.47) CRBNDDB1MEN1MAPTKMT2A
SCHEMBL31333699 0.88 DDB1 (0.47) CRBNDDB1MEN1MAPTKMT2A
SCHEMBL31333780 0.88 CRBN (0.49) CRBNDDB1HRH3
SCHEMBL27091551 0.87 DDB1 (0.60) CRBNDDB1HRH3
SCHEMBL31333636 0.87 CRBN (0.46) CRBNDDB1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed