SCHEMBL31333780

SCHEMBL31333780

CC(C)(C)OC(=O)C[C@H]1CC[C@H](N2CCN(c3ccc(NC4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 16/20 0.49
DDB1 Q16531 15/20 0.49
HRH3 Q9Y5N1 2/20 0.38
NPY2R P49146 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333732 0.94 CRBN (0.47) CRBNDDB1
SCHEMBL24126005 0.92 CRBN (0.51) CRBNDDB1
SCHEMBL31334208 0.91 CRBN (0.49) CRBNDDB1
SCHEMBL31334074 0.89 CRBN (0.47) CRBNDDB1HRH3CYP3A4
SCHEMBL31333667 0.88 CRBN (0.44) CRBNDDB1NPY2R
SCHEMBL24125412 0.88 CRBN (0.49) CRBNDDB1
SCHEMBL31333970 0.88 CRBN (0.51) CRBNDDB1HRH3
SCHEMBL31334803 0.87 CRBN (0.47) CRBNDDB1CYP3A4
SCHEMBL31334254 0.86 CRBN (0.49) CRBNDDB1HRH3
SCHEMBL31333901 0.86 DDB1 (0.61) CRBNDDB1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed