SCHEMBL31334039

SCHEMBL31334039

O=C1CCC(Nc2ccc(C3CCN(CC4CCN(C(=O)C5CCCC(Nc6ncc(Cl)c(-c7cccc(-c8ccccc8)c7)n6)C5)CC4)CC3)cc2)C(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 18/20 0.41
BTK Q06187 1/20 0.37
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333497 0.95 MAPK1 (0.41) MAPK1DDB1CRBN
SCHEMBL31334453 0.94 MAPK1 (0.41) MAPK1CRBN
SCHEMBL31333989 0.92 MAPK1 (0.46) MAPK1
SCHEMBL31335016 0.89 MAPK1 (0.49) MAPK1
SCHEMBL31334754 0.88 MAPK1 (0.45) MAPK1
SCHEMBL31334252 0.86 IKZF2 (0.51) MAPK1
SCHEMBL31334521 0.81 MAPK1 (0.38) MAPK1DDB1CRBN
SCHEMBL31333218 0.81 IKZF1 (0.49) MAPK1DDB1CRBN
SCHEMBL31335057 0.81 MAPK1 (0.38) MAPK1DDB1CRBN
SCHEMBL31333897 0.81 MAPK1 (0.45) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed