Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255932 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1MAPTHTTKMT2A | |
| SCHEMBL9781436 | 0.81 | FASN (0.50) | FASNCCNE1CDK2CCNB2CDK1 | |
| SCHEMBL8897572 | 0.77 | GRIN2D (0.65) | CTSVCTSLKDM4EALDH1A1MAPT | |
| SCHEMBL8000790 | 0.74 | PARP1 (0.57) | CTSVCTSLFASNMAPTPARP1 | |
| SCHEMBL8784156 | 0.73 | CYP1A2 (0.56) | KDM4EKMT2A | |
| SCHEMBL8001957 | 0.72 | PARP1 (0.57) | CTSVCTSLFASNKDM4EALDH1A1 | |
| SCHEMBL4827488 | 0.72 | CYP1A2 (0.62) | KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8785378 | 0.71 | FASN (0.81) | FASNKDM4EMAPTPARP1KMT2A | |
| SCHEMBL8000855 | 0.71 | PARP1 (0.67) | FASNKDM4EALDH1A1MAPTPARP1 | |
| SCHEMBL10650769 | 0.70 | PARP1 (0.46) | ALDH1A1MAPTPARP1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021333-B1 | ANTI-PROLIFERATIVE COMPOUNDS DERIVING FROM A 3-ARYL-COUMARINE OR 3-ARYL-QUINOLIN-2-ONE AND USES THEREOF | EOS ETHICAL ONCOLOGY SCIENCE S (IT) | 2010-07-14 | — | — | EP | disclosed |