Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.67 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.60 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.55 |
| ▸ | FASN | P49327 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806366 | 0.84 | PARP1 (0.58) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8000790 | 0.83 | PARP1 (0.57) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8001957 | 0.83 | PARP1 (0.57) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8785378 | 0.82 | FASN (0.81) | PARP1DAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9387713 | 0.81 | PARP1 (0.63) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7988937 | 0.81 | PARP1 (0.55) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8136947 | 0.81 | PARP1 (0.55) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7997490 | 0.80 | PARP1 (0.53) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10651016 | 0.80 | PARP1 (0.53) | PARP1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7997773 | 0.80 | PARP1 (0.53) | PARP1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |