Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333644 | 0.91 | JAK2 (0.45) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334364 | 0.88 | SYK (0.44) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333268 | 0.87 | SYK (0.46) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333776 | 0.87 | SYK (0.46) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334896 | 0.86 | SYK (0.48) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334709 | 0.86 | SYK (0.48) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334302 | 0.86 | CCNT1 (0.43) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333363 | 0.85 | ADORA1 (0.48) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333549 | 0.85 | SYK (0.42) | SYKMAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333756 | 0.85 | SYK (0.42) | SYKMAPK1CCNA2CDK2MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |