Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334302 | 0.94 | CCNT1 (0.43) | JAK2BRD4SYKMAPK1CDK2 | |
| SCHEMBL31334058 | 0.91 | SYK (0.42) | JAK2BRD4MAPK8SYKMAPK1 | |
| SCHEMBL31334740 | 0.89 | SYK (0.41) | JAK2BRD4SYKMAPK1CDK2 | |
| SCHEMBL31333363 | 0.89 | ADORA1 (0.48) | MAPK8SYKMAPK1CDK2CCNA2 | |
| SCHEMBL31333190 | 0.89 | PCSK9 (0.44) | SYKMAPK1CDK2CCNA2MAPK3 | |
| SCHEMBL31333852 | 0.89 | SYK (0.46) | MAPK8SYKMAPK1CDK2CCNA2 | |
| SCHEMBL31334573 | 0.89 | MAPK1 (0.49) | JAK2BRD4MAPK8SYKMAPK1 | |
| SCHEMBL31333268 | 0.86 | SYK (0.46) | SYKMAPK1CDK2CCNA2MAPK3 | |
| SCHEMBL31333776 | 0.86 | SYK (0.46) | SYKMAPK1CDK2CCNA2MAPK3 | |
| SCHEMBL31334462 | 0.85 | SYK (0.44) | JAK2BRD4MAPK8SYKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |