Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 6/20 | 0.42 |
| ▸ | CDK1 | P06493 | 5/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | CDK7 | P50613 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | CCNH | P51946 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334815 | 0.90 | MAP4K1 (0.45) | MAPK1MAP4K1MAPK14CDK2CDK1 | |
| SCHEMBL31334927 | 0.90 | MAP4K1 (0.45) | MAPK1MAP4K1MAPK14CDK2CDK1 | |
| SCHEMBL31334958 | 0.89 | MAPK1 (0.45) | MAPK1MAPK14CDK2CDK1CCNA2 | |
| SCHEMBL31333605 | 0.89 | MAPK1 (0.49) | MAPK1MAP4K1CDK2CDK1DYRK2 | |
| SCHEMBL31334893 | 0.88 | SYK (0.46) | MAPK1MAPK14CDK2CDK1CCNA2 | |
| SCHEMBL31334222 | 0.88 | JAK2 (0.51) | MAPK1MAPK14CDK2CDK1CCNA2 | |
| SCHEMBL31334812 | 0.88 | MAP4K1 (0.46) | MAPK1MAP4K1CDK2CCNA2PIK3CD | |
| SCHEMBL31333841 | 0.88 | MAP4K1 (0.44) | MAPK1MAP4K1CDK2CCNA2PIK3CD | |
| SCHEMBL31334700 | 0.88 | SYK (0.47) | MAPK1MAPK14CDK2CDK1CCNA2 | |
| SCHEMBL31334480 | 0.87 | MAPK1 (0.45) | MAPK1MAPK14CDK2CDK1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |