Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333681 | 0.91 | MAP4K1 (0.46) | MAP4K1MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333841 | 0.91 | MAP4K1 (0.44) | MAP4K1MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334927 | 0.90 | MAP4K1 (0.45) | MAP4K1MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334836 | 0.90 | MAP4K1 (0.43) | MAP4K1MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334815 | 0.90 | MAP4K1 (0.45) | MAP4K1MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333902 | 0.90 | MAP4K1 (0.43) | MAP4K1MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333633 | 0.90 | MAP4K1 (0.47) | MAP4K1MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334161 | 0.88 | MAPK1 (0.46) | MAP4K1MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333712 | 0.87 | SYK (0.47) | ADORA1MAPK1CDK2ADORA2AADORA2B | |
| SCHEMBL31334186 | 0.86 | PIK3CA (0.47) | ADORA1MAPK1CCNA2CDK2MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |