SCHEMBL31334182

SCHEMBL31334182

NCC1CCN(C2CCN(c3ccc4c(c3)oc(=O)n4C3CCC(=O)NC3=O)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 13/20 0.40
DDB1 Q16531 9/20 0.36
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
OPRL1 P41146 1/20 0.35
IKZF3 Q9UKT9 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
PKM P14618 1/20 0.33
TP53BP1 Q12888 1/20 0.33
L3MBTL3 Q96JM7 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IKZF2 Q9UKS7 1/20 0.32
CBX7 O95931 1/20 0.32
CDYL2 Q8N8U2 1/20 0.32
CDYL Q9Y232 1/20 0.32
ESR1 P03372 1/20 0.32
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333811 0.86 CRBN (0.40) CRBNDDB1OPRM1OPRD1OPRK1
SCHEMBL31335114 0.84 IKZF2 (0.44) CRBNDDB1IKZF2
SCHEMBL31334477 0.83 CRBN (0.41) CRBNDDB1OPRM1OPRD1OPRK1
SCHEMBL31333950 0.82 CRBN (0.40) CRBNDDB1IKZF3IKZF2ESR1
SCHEMBL31334494 0.81 CRBN (0.40) CRBNDDB1IKZF2ESR1AR
SCHEMBL31334020 0.81 CRBN (0.37) CRBNDDB1OPRM1OPRD1OPRK1
SCHEMBL30830666 0.81 CRBN (0.47) CRBNDDB1OPRM1IKZF3ALDH1A1
SCHEMBL25928719 0.81 CRBN (0.47) CRBNDDB1OPRM1IKZF3ALDH1A1
Hydrochloric Acid SCHEMBL31254124 0.80 CRBN (0.47) CRBNDDB1OPRM1IKZF3ALDH1A1
SCHEMBL30258434 0.79 CRBN (0.43) CRBNDDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed