SCHEMBL31334477

SCHEMBL31334477

CC(C)(C)OC(=O)NCC1CCN(C2CCN(c3ccc4c(c3)oc(=O)n4C3CCC(=O)NC3=O)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 8/20 0.41
DDB1 Q16531 7/20 0.41
CKS1B P61024 1/20 0.37
SKP1 P63208 1/20 0.37
SKP2 Q13309 1/20 0.37
ACACB O00763 6/20 0.37
ACACA Q13085 6/20 0.37
DRD2 P14416 1/20 0.36
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
OGFRL1 Q5TC84 1/20 0.35
AR P10275 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334020 0.87 CRBN (0.37) CRBNDDB1OPRM1OPRD1OPRK1
SCHEMBL31334423 0.87 DDB1 (0.41) CRBNDDB1DRD2
SCHEMBL31333783 0.83 CRBN (0.42) CRBNDDB1DRD2AR
SCHEMBL23541259 0.83 DDB1 (0.51) CRBNDDB1CKS1BSKP1SKP2
SCHEMBL31334182 0.83 CRBN (0.40) CRBNDDB1OPRM1OPRD1OPRK1
SCHEMBL31333811 0.81 CRBN (0.40) CRBNDDB1OPRM1OPRD1OPRK1
SCHEMBL31333449 0.81 CRBN (0.43) CRBNDDB1AR
SCHEMBL31333484 0.81 CRBN (0.48) CRBNDDB1AR
SCHEMBL30831040 0.80 CRBN (0.54) CRBNDDB1
SCHEMBL31333550 0.80 CRBN (0.38) CRBNDDB1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed