SCHEMBL31334245

SCHEMBL31334245

O=C(O)CC1CCN(C2CCN(c3ccc(NC4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 18/20 0.44
DDB1 Q16531 17/20 0.44
FFAR4 Q5NUL3 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24126007 0.95 CRBN (0.49) CRBNDDB1FFAR4
Hydrochloric Acid SCHEMBL25229847 0.94 CRBN (0.48) CRBNDDB1FFAR4
SCHEMBL31333667 0.93 CRBN (0.44) CRBNDDB1FFAR4
SCHEMBL31333201 0.90 CRBN (0.44) CRBNDDB1FFAR4
SCHEMBL24125411 0.89 CRBN (0.47) CRBNDDB1
SCHEMBL31333732 0.88 CRBN (0.47) CRBNDDB1
SCHEMBL31334519 0.88 CRBN (0.47) CRBNDDB1
SCHEMBL31333516 0.88 DDB1 (0.47) CRBNDDB1
SCHEMBL31334602 0.86 CRBN (0.47) CRBNDDB1
SCHEMBL31334636 0.85 DDB1 (0.49) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed