SCHEMBL31333732

SCHEMBL31333732

CC(C)(C)OC(=O)CC1CCN(C2CCN(c3ccc(NC4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.47
DDB1 Q16531 19/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24126005 0.95 CRBN (0.51) CRBNDDB1
SCHEMBL31333780 0.94 CRBN (0.49) CRBNDDB1
SCHEMBL24125412 0.91 CRBN (0.49) CRBNDDB1
SCHEMBL31334803 0.91 CRBN (0.47) CRBNDDB1
SCHEMBL31333823 0.89 CRBN (0.46) CRBNDDB1
SCHEMBL31334245 0.88 CRBN (0.44) CRBNDDB1
SCHEMBL31333765 0.88 CRBN (0.49) CRBNDDB1
SCHEMBL31334208 0.87 CRBN (0.49) CRBNDDB1
SCHEMBL27091551 0.87 DDB1 (0.60) CRBNDDB1
SCHEMBL25175962 0.85 CRBN (0.49) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed