Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CCND3 | P30281 | 2/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335020 | 1.00 | IRAK4 (0.40) | IRAK4CDK2CCNB2CCNE2CDK1 | |
| SCHEMBL31333244 | 0.93 | MAPK6 (0.41) | CDK2CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL31334136 | 0.92 | MAPK1 (0.39) | CDK2CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL31334356 | 0.92 | MAPK1 (0.39) | CDK2CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL31334914 | 0.91 | ROCK2 (0.45) | CDK2CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL31333692 | 0.90 | MAPK8 (0.40) | CDK2CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL31333592 | 0.89 | MAPK1 (0.40) | IRAK4CDK2CCNB2CCNE2CDK1 | |
| SCHEMBL31334668 | 0.89 | MAPK8 (0.45) | CDK2CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL31333268 | 0.88 | SYK (0.46) | IRAK4CDK2CCNB2CCNE2CDK1 | |
| SCHEMBL31333776 | 0.88 | SYK (0.46) | IRAK4CDK2CCNB2CCNE2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |