Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 5/20 | 0.52 |
| ▸ | JAK3 | P52333 | 4/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 5/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.48 |
| ▸ | JUN | P05412 | 4/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 2/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334227 | 0.90 | MAPK3 (0.55) | MAPK3JAK3BTKCDK2MAPK8 | |
| SCHEMBL31334491 | 0.89 | CDK2 (0.53) | MAPK3CDK2MAPK8MAPK9JUN | |
| SCHEMBL31334728 | 0.89 | MAPK3 (0.53) | MAPK3JAK3BTKCDK2MAPK8 | |
| SCHEMBL31334390 | 0.86 | MAPK3 (0.49) | MAPK3JAK3BTKCDK2MAPK8 | |
| SCHEMBL31334683 | 0.82 | CCNT1 (0.48) | CDK2MAPK8MAPK9JUNMAPK10 | |
| SCHEMBL31334103 | 0.82 | CCNT1 (0.48) | CDK2MAPK8MAPK9JUNMAPK10 | |
| SCHEMBL31334238 | 0.82 | MAPK3 (0.49) | MAPK3JAK3BTKCDK2MAPK8 | |
| SCHEMBL31334934 | 0.81 | MAPK3 (0.58) | MAPK3JAK3BTKCDK2MAPK8 | |
| SCHEMBL31333325 | 0.81 | MAPK3 (0.58) | MAPK3JAK3BTKCDK2MAPK8 | |
| SCHEMBL31333335 | 0.79 | CDK2 (0.56) | MAPK3CDK2MAPK8MAPK9JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |