SCHEMBL31334352

SCHEMBL31334352

CC(C)(C)OC(=O)N[C@H]1CC[C@@H](Nc2ncc(Cl)c(-c3cccc(-c4ccccc4)c3)n2)CC1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 1/20 0.51
SKP1 P63208 1/20 0.51
SKP2 Q13309 1/20 0.51
MAPK1 P28482 13/20 0.49
ADORA1 P30542 3/20 0.46
BTK Q06187 1/20 0.45
ADORA2A P29274 1/20 0.44
LIPG Q9Y5X9 1/20 0.44
KDM1A O60341 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333690 1.00 CKS1B (0.51) CKS1BSKP1SKP2MAPK1ADORA1
SCHEMBL31334026 0.93 MAPK1 (0.48) CKS1BSKP1SKP2MAPK1
SCHEMBL31333206 0.89 CKS1B (0.51) CKS1BSKP1SKP2MAPK1ADORA1
SCHEMBL31334996 0.86 ADORA1 (0.51) CKS1BSKP1SKP2MAPK1ADORA1
SCHEMBL31334822 0.86 ADORA1 (0.51) CKS1BSKP1SKP2MAPK1ADORA1
SCHEMBL31333217 0.85 MAPK8 (0.54) CKS1BSKP1SKP2MAPK1
SCHEMBL31333957 0.82 ADORA1 (0.49) MAPK1ADORA1ADORA2A
SCHEMBL31333929 0.82 ADORA1 (0.49) MAPK1ADORA1ADORA2A
SCHEMBL31334419 0.82 ADORA1 (0.53) MAPK1ADORA1ADORA2A
SCHEMBL31333299 0.82 ADORA1 (0.53) MAPK1ADORA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed