SCHEMBL31334026

SCHEMBL31334026

CC(C)(C)OC(=O)N[C@H]1CC[C@H](Nc2ncc(Cl)c(-c3cccc(-c4ccc(F)cc4)c3)n2)CC1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 18/20 0.48
CKS1B P61024 1/20 0.44
SKP1 P63208 1/20 0.44
SKP2 Q13309 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334352 0.93 CKS1B (0.51) MAPK1CKS1BSKP1SKP2
SCHEMBL31333690 0.93 CKS1B (0.51) MAPK1CKS1BSKP1SKP2
SCHEMBL31334296 0.86 MAPK1 (0.46) MAPK1
SCHEMBL31334054 0.86 CCNT1 (0.52) MAPK1
SCHEMBL31333206 0.85 CKS1B (0.51) MAPK1CKS1BSKP1SKP2
SCHEMBL31334426 0.83 MAPK1 (0.49) MAPK1
SCHEMBL31335014 0.83 CCNT1 (0.49) MAPK1
SCHEMBL31334180 0.82 CCNT1 (0.47) MAPK1
SCHEMBL31333534 0.81 MAPK1 (0.45) MAPK1
SCHEMBL31334056 0.80 CCNT1 (0.57) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed