Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 8/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.48 |
| ▸ | JUN | P05412 | 7/20 | 0.45 |
| ▸ | CDK2 | P24941 | 7/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334516 | 0.91 | MAPK1 (0.48) | MAPK1CDK2CCNT1USP30 | |
| SCHEMBL31333217 | 0.88 | MAPK8 (0.54) | MAPK1MAPK8MAPK9MAPK10JUN | |
| SCHEMBL31333588 | 0.86 | CDK4 (0.48) | MAPK1USP30CCNKCDK12 | |
| SCHEMBL31334250 | 0.85 | MAPK1 (0.49) | MAPK1MAPK8MAPK9MAPK10JUN | |
| SCHEMBL31334824 | 0.85 | MAPK1 (0.44) | MAPK1CDK2USP30 | |
| SCHEMBL31334878 | 0.84 | MAPK1 (0.41) | MAPK1MAPK8MAPK9MAPK10JUN | |
| SCHEMBL31334616 | 0.84 | MAPK8 (0.51) | MAPK1MAPK8MAPK9MAPK10JUN | |
| SCHEMBL31334054 | 0.83 | CCNT1 (0.52) | MAPK1MAPK8MAPK9MAPK10JUN | |
| SCHEMBL31333721 | 0.83 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL31335065 | 0.83 | MAPK1 (0.45) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |