SCHEMBL31334375

SCHEMBL31334375

CC(C)(C)OC(=O)[C@H]1CC[C@H](Nc2ncc(F)c(-c3cccc(C(=O)O)c3)n2)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.47
CSNK2A2 P19784 4/20 0.45
CSNK2B P67870 4/20 0.45
DYRK2 Q92630 4/20 0.41
ADORA1 P30542 2/20 0.40
CSNK2A1 P68400 6/20 0.40
MCHR1 Q99705 2/20 0.40
ADRA2A P08913 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
HTR2B P41595 1/20 0.40
FLT3 P36888 1/20 0.40
TYRO3 Q06418 1/20 0.40
MERTK Q12866 1/20 0.40
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
CSNK2A3 Q8NEV1 1/20 0.39
USP30 Q70CQ3 1/20 0.38
CDK4 P11802 1/20 0.38
CCND1 P24385 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333311 0.92 MAPK1 (0.46) MAPK1CSNK2A2CSNK2BDYRK2ADORA1
SCHEMBL31333860 0.92 MAPK1 (0.49) MAPK1CSNK2A2CSNK2BDYRK2ADORA1
SCHEMBL31333816 0.89 MAPK1 (0.47) MAPK1CSNK2A2CSNK2BDYRK2ADORA1
SCHEMBL31334005 0.88 MAPK1 (0.47) MAPK1CSNK2A2CSNK2BDYRK2ADORA1
SCHEMBL31333642 0.85 DYRK2 (0.45) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31334517 0.83 CSNK2A2 (0.49) CSNK2A2CSNK2BADORA1CSNK2A1MCHR1
SCHEMBL31334084 0.81 MAPK1 (0.46) MAPK1DYRK2ADORA1MCHR1ADRA2A
SCHEMBL31333206 0.81 CKS1B (0.51) MAPK1CSNK2A2CSNK2BDYRK2ADORA1
SCHEMBL31333408 0.80 DYRK2 (0.48) MAPK1CSNK2A2CSNK2BDYRK2CDK4
SCHEMBL31334719 0.78 ADORA1 (0.47) MAPK1CSNK2A2CSNK2BADORA1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed