SCHEMBL31334005

SCHEMBL31334005

CC(C)(C)OC(=O)[C@H]1CC[C@H](Nc2ncc(F)c(-c3cccc(C4CC4)c3)n2)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 7/20 0.47
DYRK2 Q92630 5/20 0.39
CDK4 P11802 2/20 0.38
CCND1 P24385 2/20 0.38
CCND3 P30281 2/20 0.38
CDK6 Q00534 2/20 0.38
ADORA1 P30542 2/20 0.37
CDK2 P24941 2/20 0.37
CCNB2 O95067 1/20 0.37
CCNE2 O96020 1/20 0.37
CDK1 P06493 1/20 0.37
CCNB1 P14635 1/20 0.37
CCNE1 P24864 1/20 0.37
CDK5 Q00535 1/20 0.37
CDK5R1 Q15078 1/20 0.37
CCNB3 Q8WWL7 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
ADORA2A P29274 1/20 0.37
MCHR1 Q99705 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333860 0.90 MAPK1 (0.49) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31333445 0.89 MAPK1 (0.47) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31334375 0.88 MAPK1 (0.47) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31333311 0.87 MAPK1 (0.46) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31333233 0.86 NPC1 (0.43) MAPK1ADORA1CDK2CCNB2CCNE2
SCHEMBL31333197 0.85 MAPK3 (0.41) MAPK1CDK4CCND1ADORA1CDK2
SCHEMBL31334579 0.84 MAPK1 (0.42) MAPK1ADORA1CDK2CCNB2CCNE2
SCHEMBL31334783 0.83 MAPK8 (0.45) MAPK1ADORA1CDK2CCNB2CCNE2
SCHEMBL31333951 0.82 ADORA1 (0.41) MAPK1CDK4CCND1CCND3CDK6
SCHEMBL31333944 0.80 ADORA1 (0.49) CDK4CCND1CCND3CDK6ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed