SCHEMBL31334513

SCHEMBL31334513

COc1ncccc1-n1cc(Br)cn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.43
SLC2A1 P11166 1/20 0.40
SLC2A2 P11168 1/20 0.40
SLC2A3 P11169 1/20 0.40
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
DRD3 P35462 1/20 0.36
APLNR P35414 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MEN1 O00255 1/20 0.34
PKM P14618 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP46A1 Q9Y6A2 1/20 0.34
SMO Q99835 1/20 0.33
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26114951 0.76 PRKCI (0.46) PRKCIKDM4EALDH1A1HPGDMEN1
SCHEMBL510020 0.76 PRKCI (0.46) PRKCIKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL18074982 0.76 SLC2A1 (0.42) PRKCISLC2A1SLC2A2SLC2A3DRD2
SCHEMBL26342753 0.74 NPC1 (0.45) SLC2A1SLC2A2SLC2A3APLNRKDM4E
SCHEMBL31333631 0.73 FFAR1 (0.40) SLC2A1SLC2A2SLC2A3APLNR
SCHEMBL31334840 0.72 RPS6KA5 (0.37) SLC2A1SLC2A2SLC2A3APLNRKDM4E
SCHEMBL671958 0.70 ELANE (0.47) PRKCIALDH1A1HPGDSMN1; SMN2
SCHEMBL6694090 0.69 PRKCI (0.41) PRKCIKDM4EALDH1A1HPGDMEN1
SCHEMBL1198582 0.69 PRKCI (0.42) PRKCIDRD2DRD4DRD3KDM4E
SCHEMBL510901 0.69 PRKCI (0.40) PRKCIKDM4EALDH1A1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed