Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18074948 | 0.83 | PRKCI (0.39) | PRKCIMEN1PKMKMT2AALDH1A1 | |
| SCHEMBL950266 | 0.83 | ALDH1A1 (0.44) | PRKCIKMT2AALDH1A1TRPV1CYP1A2 | |
| SCHEMBL18394013 | 0.83 | PDE10A (0.34) | MEN1PKMKMT2AAXLALDH1A1 | |
| SCHEMBL12699417 | 0.83 | PLAU (0.42) | PRKCIMEN1PKMKMT2AALDH1A1 | |
| SCHEMBL18074982 | 0.79 | SLC2A1 (0.42) | PRKCIMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1198582 | 0.75 | PRKCI (0.42) | PRKCIMEN1PKMKMT2AAXL | |
| SCHEMBL20394404 | 0.74 | ADORA2A (0.45) | MEN1KMT2AAXLALDH1A1KDM4E | |
| SCHEMBL3923413 | 0.73 | ALKBH2 (0.57) | PRKCIMEN1KMT2AKDM4EMAPT | |
| SCHEMBL18074947 | 0.73 | POLB (0.33) | PRKCIKMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL26114951 | 0.72 | PRKCI (0.46) | PRKCIMEN1PKMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030637-A2 | TREATMENT OF OBESITY AND OTHER DISORDERS ASSOCIATED WITH EXCESSIVE FOOD INTAKE | MERCK & CO., INC. (US) | 2004-04-15 | — | — | WO | disclosed |