Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 9/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 7/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | JUN | P05412 | 3/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334274 | 0.94 | MAPK1 (0.46) | MAPK1EGFRBTKCDK2CDK1 | |
| SCHEMBL31333189 | 0.89 | MAPK8 (0.52) | MAPK1CDK2JUNMAPK8MAPK9 | |
| SCHEMBL31333385 | 0.89 | MAPK8 (0.52) | MAPK1CDK2JUNMAPK8MAPK9 | |
| SCHEMBL31334440 | 0.87 | IRAK1 (0.49) | MAPK1EGFRBTKCDK2CDK1 | |
| SCHEMBL31333426 | 0.87 | MAPK1 (0.44) | MAPK1EGFRBTKCDK2CDK1 | |
| SCHEMBL31333403 | 0.86 | MAPK1 (0.46) | MAPK1CDK2CCNE1JUNMAPK8 | |
| SCHEMBL31334224 | 0.85 | MAPK1 (0.49) | MAPK1CDK2JUNMAPK8MAPK9 | |
| SCHEMBL31334037 | 0.84 | MAPK1 (0.45) | MAPK1CDK2CDK1CCNB1CCNE1 | |
| SCHEMBL31334719 | 0.81 | ADORA1 (0.47) | MAPK1CDK2CDK1CCNB1CCNE1 | |
| SCHEMBL31334890 | 0.81 | ADORA1 (0.47) | MAPK1CDK2CDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |