SCHEMBL31334598

SCHEMBL31334598

CC(C)(O)c1cc(-c2nc(NC3CCCC(C(=O)O)C3)ncc2F)ccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK3 P27361 3/20 0.41
MAPK1 P28482 4/20 0.39
CDK4 P11802 4/20 0.37
CCND1 P24385 4/20 0.37
CCND3 P30281 4/20 0.37
CDK6 Q00534 4/20 0.37
DGAT2 Q96PD7 1/20 0.36
CDK2 P24941 2/20 0.36
CCNB2 O95067 1/20 0.36
CCNE2 O96020 1/20 0.36
CDK1 P06493 1/20 0.36
CCNB1 P14635 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
CCNB3 Q8WWL7 1/20 0.36
DYRK2 Q92630 3/20 0.35
SYK P43405 2/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333651 0.92 MAPK3 (0.39) MAPK3MAPK1CDK4CCND1CCND3
SCHEMBL31334490 0.91 MAPK1 (0.40) MAPK3MAPK1CDK4CCND1CCND3
SCHEMBL31333798 0.91 MAPK1 (0.40) MAPK3MAPK1CDK4CCND1CCND3
SCHEMBL31334321 0.90 MAPK1 (0.42) MAPK3MAPK1CDK4CCND1CCND3
SCHEMBL31333665 0.83 MAPK1 (0.42) MAPK3MAPK1CDK4CCND1CCND3
SCHEMBL31333890 0.83 MAPK1 (0.43) MAPK3MAPK1CDK4CCND1CCND3
SCHEMBL31333526 0.83 MAPK1 (0.43) MAPK3MAPK1CDK4CCND1CCND3
SCHEMBL31334985 0.82 MAPK8 (0.44) MAPK3MAPK1CDK4CCND1CCND3
SCHEMBL31334123 0.82 MAPK3 (0.47) MAPK3MAPK1CDK2CCNE1ADORA2A
SCHEMBL31333476 0.81 CDK9 (0.46) MAPK3MAPK1CDK4CCND1CCND3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed