SCHEMBL31334665

SCHEMBL31334665

Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(C3CCN(C4CCN(CC(=O)N5CCC(Nc6ncc(Cl)c(-c7cccc(-c8ccccc8)c7)n6)CC5)CC4)CC3)cc21

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 19/20 0.44
JUN P05412 1/20 0.37
CDK2 P24941 1/20 0.37
MAPK8 P45983 1/20 0.37
MAPK9 P45984 1/20 0.37
MAPK10 P53779 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333715 0.94 MAPK1 (0.44) MAPK1JUNCDK2MAPK8MAPK9
SCHEMBL31334334 0.94 MAPK1 (0.41) MAPK1JUNCDK2MAPK8MAPK9
SCHEMBL31333626 0.93 MAPK1 (0.44) MAPK1JUNCDK2MAPK8MAPK9
SCHEMBL31334165 0.91 MAPK1 (0.39) MAPK1
SCHEMBL31334794 0.90 MAPK1 (0.41) MAPK1JUNCDK2MAPK8MAPK9
SCHEMBL31333312 0.90 MAPK1 (0.41) MAPK1
SCHEMBL31333319 0.89 MAPK1 (0.40) MAPK1
SCHEMBL31334361 0.89 MAPK1 (0.41) MAPK1
SCHEMBL31333237 0.89 MAPK1 (0.42) MAPK1
SCHEMBL31334680 0.87 MAPK1 (0.41) MAPK1JUNCDK2MAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed